Arnd Heuser Selected Research

PR-957

1/2020	ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage.
1/2020	Heart-Specific Immune Responses in an Animal Model of Autoimmune-Related Myocarditis Mitigated by an Immunoproteasome Inhibitor and Genetic Ablation.
1/2018	The immunoproteasome-specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis.

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Arnd Heuser Research Topics

Disease

7	Fibrosis (Cirrhosis) 01/2020 - 02/2008
7	Inflammation (Inflammations) 01/2020 - 08/2009
6	Hypertension (High Blood Pressure) 01/2020 - 02/2008
5	Myocarditis (Carditis) 01/2021 - 01/2018
4	Heart Failure 01/2020 - 05/2008
4	Cardiomegaly (Heart Hypertrophy) 01/2020 - 02/2008
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 09/2009 - 06/2006
2	Sepsis (Septicemia) 12/2021 - 01/2018
2	Infections 01/2021 - 01/2020
2	Neoplasms (Cancer) 01/2020 - 04/2016
2	Thrombosis (Thrombus) 01/2016 - 08/2009
2	Atrial Remodeling 11/2014 - 02/2008
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 06/2008 - 12/2005
1	Cardiomyopathies (Cardiomyopathy) 12/2021
1	Atrophy 12/2021
1	Lung Diseases (Lung Disease) 01/2021
1	Pancreatitis 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Brachydactyly with hypertension 01/2020
1	Pre-Eclampsia (Preeclampsia) 01/2020
1	Essential Hypertension 01/2020
1	Albuminuria 01/2020
1	Stroke (Strokes) 01/2020
1	Crohn Disease (Crohn's Disease) 11/2018
1	Colitis 11/2018
1	Polyuria 01/2018
1	Heart Diseases (Heart Disease) 01/2018
1	Body Weight (Weight, Body) 08/2017
1	Obesity 08/2017
1	Multiple Myeloma 04/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2016
1	Neointima 01/2016
1	Muscular Diseases (Myopathy) 01/2016
1	Atherosclerosis 01/2016
1	Hypertrophy 04/2015
1	Acute Liver Failure (Fulminant Hepatic Failure) 08/2012
1	Liver Failure 08/2012
1	AIDS-Related Complex (ARC) 08/2012

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 12/2021 - 11/2004
3	PR-957IBA 01/2020 - 01/2018
3	Pharmaceutical PreparationsIBA 01/2018 - 01/2016
3	Angiotensin IIIBA 04/2015 - 09/2009
2	ChemokinesIBA 01/2020 - 01/2018
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 04/2016
2	ReninIBA 01/2020 - 02/2008
2	AngiotensinsIBA 11/2014 - 02/2010
2	ConnectinIBA 09/2009 - 06/2006
1	Myosins (Myosin)IBA 12/2021
1	salicylhydroxamic acid (SHAM)IBA 12/2021
1	ChitinasesIBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021
1	Tramadol (K315)FDA LinkGeneric 01/2021
1	empagliflozinIBA 01/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020
1	Pravastatin (Pravachol)FDA LinkGeneric 01/2020
1	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 01/2020
1	AngiotensinogenIBA 01/2020
1	SaltsIBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 01/2020
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 11/2018
1	Dextrans (Dextran)FDA Link 11/2018
1	DesmogleinsIBA 11/2018
1	villinIBA 11/2018
1	DesmocollinsIBA 11/2018
1	Cadherins (E-Cadherin)IBA 11/2018
1	BradykininIBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Ion Channels (Ion Channel)IBA 01/2018
1	CytokinesIBA 01/2018
1	Macrophage Colony-Stimulating FactorIBA 01/2018
1	Vasopressins (Vasopressin)IBA 01/2018
1	Soluble Guanylyl CyclaseIBA 01/2018
1	Cell Adhesion Molecule-1IBA 08/2017
1	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 08/2017
1	AnthracyclinesIBA 04/2016
1	Antineoplastic Agents (Antineoplastics)IBA 04/2016
1	carfilzomibIBA 04/2016
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2016
1	Protein AggregatesIBA 01/2016
1	MetalsIBA 01/2016
1	Phenobarbital (Luminal)FDA Link 01/2016
1	LigandsIBA 01/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2016
1	Death Domain ReceptorsIBA 08/2012
1	LipopolysaccharidesIBA 08/2012
1	GalactosamineIBA 08/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2012
1	Concanavalin AIBA 08/2012
1	AutoantibodiesIBA 02/2010
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 09/2009
1	Desoxycorticosterone Acetate (DOCA)FDA Link 08/2009

Therapy/Procedure

3	Therapeutics 01/2020 - 08/2012
1	Ligation 12/2021
1	Punctures 12/2021
1	Analgesia 01/2021
1	Stents 01/2016